Aligned Modern Health Builds a National Holistic Care Model

Aligned Modern Health is a Chicago-founded healthcare provider building a broader access model for functional medicine, hormone health, peptide therapy, chiropractic care, acupuncture, and massage therapy. Virginia Materese leads the company as CEO, while Brian Carey, Andrew Ingley, William Fiely, and Ryan O'Toole founded the business in 2010.

The company operates a network of 15-plus clinics around Chicago and provides virtual care in more than 20 states. Its model combines clinicians, diagnostics, personalized care plans, insurance participation, and digital access for patients navigating chronic, hormonal, metabolic, and musculoskeletal concerns.

Aligned Modern Health matters now because it is testing whether personalized, multidisciplinary care can scale beyond a regional clinic network without turning into a premium service reserved for a narrow self-pay market. A new majority growth investment from Arcventis Health Partners gives the company capital and operating support for that test.

About Aligned Modern Health

Aligned Modern Health began in Chicago in 2010. The company was built around a simple frustration with a complicated consequence: patients with overlapping symptoms are often sent through separate appointments, specialties, tests, and treatment plans that do not naturally connect.

The company's response is a coordinated care model spanning functional medicine, hormone health, chiropractic physical medicine, acupuncture, massage therapy, and newer peptide protocols. Official materials describe a clinical team of more than 100 doctors, nurse practitioners, and clinicians.

That breadth is not automatically an advantage. A menu becomes valuable only when providers share context, records move cleanly, and patients understand who owns the next decision. Aligned Modern Health is trying to make coordination itself part of the product.

The problem Aligned Modern Health is solving

Persistent symptoms rarely respect the organizational chart of a healthcare system. Fatigue can overlap with sleep, hormones, nutrition, metabolic health, stress, medication, and chronic disease. Pain can involve movement, inflammation, recovery, and behavior. Patients experience one body, even when the system bills in separate departments.

Aligned Modern Health positions its model between conventional episodic care and the expensive self-pay world that has grown around longevity and personalized medicine. The company says it accepts major insurance plans for visits and bloodwork while also supporting self-pay and FSA/HSA options.

Insurance participation matters because access is part of the strategy, not a footnote. It can widen the addressable patient population, but it also adds reimbursement rules, documentation requirements, eligibility checks, and network management. The operational burden arrives with the commercial opportunity.

From Chicago clinics to virtual care

Aligned Modern Health's locations network remains anchored in Chicago and its suburbs. Physical clinics support services that benefit from hands-on treatment or local diagnostics, while virtual care extends functional medicine and hormone health to patients across more than 20 states.

The virtual layer is where the company starts to look less like a regional practice and more like a care platform. It also creates the harder version of the business. According to U.S. Department of Health and Human Services guidance, telehealth is generally regulated where the patient is located. Expansion therefore depends on state-aware protocols, appropriately licensed clinicians, provider availability, and consistent oversight.

Video is the easy part. The real infrastructure is clinical capacity, documentation, compliance, scheduling, and continuity across a larger map.

Leadership and the next operating chapter

Virginia Materese became CEO in 2023 after more than 15 years in senior healthcare leadership. Before Aligned Modern Health, she managed large multisite operations, including a national network of orthopedic, neurosurgery, physical therapy, spine, and imaging centers.

That background fits the company's present challenge. Aligned Modern Health does not need only brand awareness. It needs operating discipline across clinics, virtual care, clinical recruiting, reimbursement, and a growing service portfolio.

The founding team established the original Chicago model. Materese is now responsible for making it travel. The company must preserve the time, context, and coordination that make personalized care attractive while adding enough process to deliver those qualities consistently.

Why the Arcventis investment matters

On September 24, 2026, Arcventis Health Partners announced a majority growth investment in Aligned Modern Health. Harbour Point Capital, an earlier backer, remains a meaningful investor. The amount and valuation were not disclosed.

The company says the partnership will support national expansion, broader clinical offerings, investment in the digital patient experience, and growth of provider and clinical teams. Aligned Modern Health introduced hormone replacement therapy for men and women in 2025 and launched peptide therapy in 2026.

The financing is therefore less about adding one service than building the operating layer beneath several of them. Arcventis and Harbour Point are backing a healthcare services platform whose value depends on how well those services work together.

Hiring is a capacity signal

Aligned Modern Health's current careers page lists clinical and operational roles across functional medicine, hormone health, chiropractic care, acupuncture, massage therapy, and clinic operations. Specific openings can change, but the pattern is clear: the company is hiring the people required to turn geographic demand into actual appointment capacity.

In healthcare, growth cannot be separated from labor. A marketing campaign can create leads overnight. Licensed clinical supply moves more slowly. Every new state or service line needs qualified providers, scheduling coverage, clinical coordination, and management support.

That makes hiring a market signal rather than a recruiting slogan. Aligned Modern Health is building for more demand, but the rate of expansion will be shaped by how quickly it can add clinicians without weakening supervision or continuity.

What Aligned Modern Health signals for healthcare

Consumers are asking for more context, more time, and more coordination around chronic symptoms, hormone changes, metabolic health, recovery, and longevity. At the same time, employers, payers, and investors want care models that can expand without reproducing the fragmentation patients already dislike.

Aligned Modern Health sits directly inside that tension. Its opportunity is to make multidisciplinary care easier to access through insurance, clinics, and telehealth. Its risk is that scale turns a coordinated model into another collection of disconnected services.

The company now has experienced leadership, more than 100 clinicians, an active hiring engine, a growing virtual footprint, and new investor support. The next proof point is not simply opening more markets. It is making a patient in a new state feel that the care model still knows where the story started.